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penA penA BPSL0730 BPSL0730 BPSL1710 BPSL1710 BPSS0200 BPSS0200 BPSS0945 BPSS0945 oxa oxa ftsI-3 ftsI-3 BPSS0944 BPSS0944 BPSS0948 BPSS0948 ftsI ftsI amrA amrA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
penABeta-lactamase precursor; Similar to Yersinia enterocolitica beta-lactamase precursor BlaA SWALL:BLAC_YEREN (SWALL:Q01166) (294 aa) fasta scores: E(): 1.5e-60, 57.43% id in 289 aa. Previously sequenced as Burkholderia pseudomallei class A beta-lactamase PenA or Bla-BPS-1d SWALL:Q932Y0 (EMBL:AY032872) (295 aa) fasta scores: E(): 4.9e-114, 100% id in 295 aa. (295 aa)    
Predicted Functional Partners:
BPSL0730
Family S45 unassigned peptidase; Similar to Pseudomonas sp. penicillin acylase II precursor AcyII SWALL:PAC2_PSES3 (SWALL:P15558) (773 aa) fasta scores: E(): 4.1e-30, 29.28% id in 782 aa, and to Xanthomonas campestris penicillin acylase II AcyII or xcc1392 SWALL:AAM40690 (EMBL:AE012238) (828 aa) fasta scores: E(): 5.1e-43, 40.81% id in 838 aa, and to Xanthomonas axonopodis penicillin acylase II acyII or xac1437 SWALL:AAM36308 (EMBL:AE011775) (569 aa) fasta scores: E(): 1e-41, 41.78% id in 572 aa; possible alternative start site at codon 71.
     
  0.900
BPSL1710
Putative non-ribosomal peptide synthase (fragment); 1 probable transmembrane helix predicted for BPSL1709 by TMHMM2.0 at aa 105-127.
     
  0.900
BPSS0200
Similar to Brucella abortus putative penicillin acylase II batn1953.orf25 SWALL:Q8VQK2 (EMBL:AF454951) (761 aa) fasta scores: E(): 6e-37, 29.86% id in 817 aa, and to Arthrobacter viscosus penicillin G acylase precursor Pac or Pa SWALL:PAC_ARTVI (SWALL:P31956) (802 aa) fasta scores: E(): 1.3e-33, 27.75% id in 544 aa.
     
  0.900
BPSS0945
Subfamily M23B unassigned peptidase; Similar to the C-terminal regions of Escherichia coli, and Shigella flexneri lipoprotein NlpD precursor SWALL:NLPD_ECOLI (SWALL:P33648) (379 aa) fasta scores: E(): 1.3e-12, 32.25% id in 310 aa, and to Rhodocyclus gelatinosus NlpD protein SWALL:Q9JP90 (EMBL:AB034704) (314 aa) fasta scores: E(): 1.4e-28, 42.95% id in 305 aa.
 
   
 0.747
oxa
Beta-lactamase precursor; Almost identical to the previously sequenced Burkholderia pseudomallei beta-lactamase precursor Oxa SWALL:CAD32565 (EMBL:AJ488303) (269 aa) fasta scores: E(): 2.2e-111, 99.62% id in 269 aa. Similar to Pseudomonas aeruginosa beta-lactamase Oxa-18 precursor SWALL:BLOI_PSEAE (SWALL:O07293) (275 aa) fasta scores: E(): 2.4e-37, 43.07% id in 267 aa.
     
 0.604
ftsI-3
Putative penicillin-binding protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
     
 0.555
BPSS0944
LysR family regulatory protein; Similar to Chromatium vinosum rubisco operon transcriptional regulator RbcR SWALL:RBCR_CHRVI (SWALL:P25544) (302 aa) fasta scores: E(): 2.5e-13, 24.54% id in 273 aa, and to Ralstonia solanacearum probable transcription regulator protein rsp1267 or rs05312 SWALL:Q8XQG0 (EMBL:AL646083) (294 aa) fasta scores: E(): 3.8e-64, 57.73% id in 291 aa; Belongs to the LysR transcriptional regulatory family.
      
 0.497
BPSS0948
LysR family regulatory protein; Similar to Escherichia coli glycine cleavage system transcriptional activator GcvA SWALL:GCVA_ECOLI (SWALL:P32064) (305 aa) fasta scores: E(): 1.6e-32, 37.93% id in 290 aa, and to Pseudomonas putida putative transcriptional regulator PP1393 SWALL:AAN67016 (EMBL:AE016779) (291 aa) fasta scores: E(): 4.4e-49, 51.86% id in 268 aa; Belongs to the LysR transcriptional regulatory family.
      
 0.493
ftsI
Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
     
 0.473
amrA
Almost identical to Burkholderia pseudomallei putative membrane fusion protein AmrA SWALL:O87935 (EMBL:AF072887) (399 aa) fasta scores: E(): 7.7e-133, 99.74% id in 399 aa. Similar to Escherichia coli, and Escherichia coli O157:H7 acriflavine resistance protein A precursor AcrA or MtcA or Lir or b0463 or z0578 or ecs0516 SWALL:ACRA_ECO57 (SWALL:P31223) (397 aa) fasta scores: E(): 3.5e-43, 40.1% id in 384 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
      
 0.410
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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